Case reports

Chapter II.1: Tears Film
Dry eye
Soft contact lens with dehydrated area

Soft contact lens with dehydrated area

Dryness and contact lenses

Dryness and contact lenses

Dry eye disease with a punctal plug (closure of the tear duct)
Dry eye disease with a punctal plug (occlusion of the tear duct)

Dry eye disease with a punctal plug (occlusion of the tear duct)

Punctum Plug with high magnification

Punctum Plug with high magnification

Chapter II.3: Eyelids
Inflammation of the eyelid (blepharitis)
Inflammation of the eyelid (blepharitis) Grade 1

Inflammation of the eyelid (blepharitis) Grade 1

Inflammation of the eyelid (blepharitis) Grade 4

Inflammation of the eyelid (blepharitis) Grade 4

Allergic inflammation of the cutaneous eyelid (contact eczema) caused by intolerance to lens care products
Allergic inflammation of the cutaneous eyelid

Allergic inflammation of the cutaneous eyelid

Allergic inflammation of the cutaneous eyelid

Allergic inflammation of the cutaneous eyelid

Incomplete eyelid closure
Incomplete eyelid closure (schematic)

Incomplete eyelid closure (schematic)

Incomplete eyelid closure

Incomplete eyelid closure

Chapter II.4: Conjunctiva
Contact lens-induced papillary conjunctivitis (CLIPC) of the superior tarsal conjunctiva
CLIPC - Grade 4

CLIPC - Grade 4

CLIPC - Grade 4

CLIPC - Grade 4

Keratoconjunctivitis epidemica (KCE)
Right Eye: Grade 0

Right Eye: Grade 0

Left Eye: Grade 4

Left Eye: Grade 4

Mechanically caused contact lens-induced conjunctivitis
Local conjunctival injection Grade 3

Local conjunctival injection Grade 3

Irritation-free zone conjunctiva superior (same eye)

Irritation-free zone conjunctiva superior (same eye)

Conjunctival punctate keratitis due to edge defects in a hydrogel contact lens
Conjunctival punctate keratitis

Conjunctival punctate keratitis

Edge defect in a hydrogel contact lens

Edge defect in a hydrogel contact lens

Pinguecula
Drawing of pinguecula

Drawing of pinguecula

Prominent pinguecula

Prominent pinguecula

Pterygium
Drawing of pterygium

Drawing of pterygium

Pterygium with injection

Pterygium with injection

Conjunctival nevi
Nevus at 3 o’clock

Nevus at 3 o’clock

Nevus in the limbal region at 6 o’ clock

Nevus in the limbal region at 6 o’ clock

Hyposphagma
Severe local redness observable in primary eye position

Severe local redness observable in primary eye position

Severe local redness observable when patient looks sideways

Severe local redness observable when patient looks sideways

Conjunctival Epithelial Fold (CEF)
Stain from a too tightly fitting soft contact lens

Stain from a too tightly fitting soft contact lens

Heavy stain with conjunctival epithelial flap (CEF) from wearing a soft contact lens

Heavy stain with conjunctival epithelial flap (CEF) from wearing a soft contact lens

Chapter II.5: Cornea
3/9 o’clock punctate keratitis
3/9 o’clock punctate keratitis (schematic)

3/9 o’clock punctate keratitis (schematic)

Grade 3 central and peripheral punctate keratitis, confluent at 4 o’clock

Grade 3 central and peripheral punctate keratitis, confluent at 4 o’clock

Localized punctate keratitis in the lower third of the cornea with desiccation
Localized punctate keratitis with desiccation (schematic)

Localized punctate keratitis with desiccation (schematic)

Localized punctate keratitis, Grade 2

Localized punctate keratitis, Grade 2

Punctate keratitis
Superficial, diffuse punctate keratitis (schematic)

Superficial, diffuse punctate keratitis (schematic)

Diffuse punctate keratitis, Grade 2

Diffuse punctate keratitis, Grade 2

Central punctate keratitis due to a non-moving (binding) rigid contact lens
Central punctate keratitis (schematic)

Central punctate keratitis (schematic)

Central punctate keratitis, Grade 3, with impression left by the edge of the contact lens

Central punctate keratitis, Grade 3, with impression left by the edge of the contact lens

Solution Induced Corneal Staining (SICS)
Deep, diffuse punctate keratitis (schematic)

Deep, diffuse punctate keratitis (schematic)

Grade 4 punctate keratitis due to a toxic reaction

Grade 4 punctate keratitis due to a toxic reaction

Deep, diffuse punctate keratitis due to toxic reactions
SICS - diffuse distribution

SICS - diffuse distribution

SICS often occurs in connection with punctate keratitis

SICS often occurs in connection with punctate keratitis

Air bubble dimple veiling
Air bubble dimple veiling (schematic)

Air bubble dimple veiling (schematic)

Air bubble dimple veiling, without lens

Air bubble dimple veiling, without lens

Air bubble dimple veiling beneath rigid contact lenses with fluorescein

Air bubble dimple veiling beneath rigid contact lenses with fluorescein

Air bubble dimple veiling beneath rigid contact lenses

Air bubble dimple veiling beneath rigid contact lenses

Mucin Balls
Mucin balls under silicon hydrogel lenses with white light

Mucin balls under silicon hydrogel lenses with white light

Impressions from mucin balls without contact lenses, after staining with fluorescein

Impressions from mucin balls without contact lenses, after staining with fluorescein

Impressions from foreign objects under rigid contact lenses
Impression from a foreign object (schematic)

Impression from a foreign object (schematic)

“Scoring” from a foreign object

“Scoring” from a foreign object

Imprint of a hair

Imprint of a hair

Deep foreign object impression

Deep foreign object impression

Superior Epithelial Arcuate Lesion (SEAL)
SEAL in white light

SEAL in white light

SEAL after being stained with fluorescein

SEAL after being stained with fluorescein

Erosions
Erosion (schematic)

Erosion (schematic)

Extensive corneal erosion

Extensive corneal erosion

Epithelial oedema
“Halo vision” in cases of corneal oedema

“Halo vision” in cases of corneal oedema

Microcysts and vacuoles, Grade 3

Microcysts and vacuoles, Grade 3

Striae and folds
Striae and folds, Grade 3

Striae and folds, Grade 3

Individual striae

Individual striae

Stromal oedema (CCC: central corneal clouding)
Pronounced CCC with PMMA contact lenses

Pronounced CCC with PMMA contact lenses

CCC after removing contact lenses

CCC after removing contact lenses

Neovascularization
Beginnings of vascularization around 12 o’clock

Beginnings of vascularization around 12 o’clock

Massive corneal damage with grade 4 neovascularization

Massive corneal damage with grade 4 neovascularization

Sterile infiltrate (AIK)
AIK (schematic)

AIK (schematic)

Peripheral infiltrate at 6 o’clock

Peripheral infiltrate at 6 o’clock

Infiltrates
IK (schematic)

IK (schematic)

Infiltrate at 5 o’clock with typical limbal injection

Infiltrate at 5 o’clock with typical limbal injection

Corneal ulcer
MK (schematic)

MK (schematic)

Central corneal ulcer

Central corneal ulcer

Keratitis dendritica (herpes simplex virus keratitis)
Active herpes infection with tree-shaped epithelial lesions

Active herpes infection with tree-shaped epithelial lesions

Subepithelial scarring zone following secondary infection

Subepithelial scarring zone following secondary infection

Scars following keratoconjunctivitis epidemica (KCE)
Central nummuli following KCE

Central nummuli following KCE

Central nummuli at high magnification

Central nummuli at high magnification

Scars resulting from traumatic impact
Central corneal scar of traumatic origin in side view

Central corneal scar of traumatic origin in side view

Angular corneal tear at 5 o'clock with wrinkling

Angular corneal tear at 5 o'clock with wrinkling

Scars in keratoconus
Corneal scars with Descemet’s folds in keratoconus

Corneal scars with Descemet’s folds in keratoconus

Corneal scar in grade 4 keratoconus in lateral view

Corneal scar in grade 4 keratoconus in lateral view

Example case: Scars following keratoplasty for keratoconus
Corneal transplant with lateral observation

Corneal transplant with lateral observation

Scars from T-incisions 12 months post surgery (40-fold)

Scars from T-incisions 12 months post surgery (40-fold)

Precipitates
Precipitates in an optical slice

Precipitates in an optical slice

Precipitates in an optical section

Precipitates in an optical section

Chapter III.3: Deposits
Lipid deposits
Lipid drops in the tear film (200-fold magnification with endothelial microscope attachment)

Lipid drops in the tear film (200-fold magnification with endothelial microscope attachment)

Lipid drops on the frontal surface of the lens

Lipid drops on the frontal surface of the lens

Protein deposits
Extensive protein deposit, 6-fold magnification, dark field

Extensive protein deposit, 6-fold magnification, dark field

Netlike protein deposits, 6-fold magnification, dark field

Netlike protein deposits, 6-fold magnification, dark field

Mucin balls
Mucous substances (mucins) on the surface of a hydrogel lens (SEM image)

Mucous substances (mucins) on the surface of a hydrogel lens (SEM image)

Deposit at 9 o’clock in the lenticular area of a rigid contact lens (+6.0dpt)

Deposit at 9 o’clock in the lenticular area of a rigid contact lens (+6.0dpt)

Chapter III.4: Deposits
Cosmetics residue
Hydrophobic areas on rigid contact lenses due to eyeliner residue

Hydrophobic areas on rigid contact lenses due to eyeliner residue

Cosmetic residue on a soft contact lens

Cosmetic residue on a soft contact lens

Discolouration of the contact lens material
Peripheral metal deposit with discoloration from nicotine, 50-fold magnification, bright field

Peripheral metal deposit with discoloration from nicotine, 50-fold magnification, bright field

Central metal deposit with discolouration

Central metal deposit with discolouration

Fungal infestation
Aspergillus niger, 200-fold magnification, bright field

Aspergillus niger, 200-fold magnification, bright field

Aspergillus niger (cross-section of penetration through the contact lens)

Aspergillus niger (cross-section of penetration through the contact lens)

Aspergillus niger, penetration in lens matrix (SEM image)

Aspergillus niger, penetration in lens matrix (SEM image)

Candida albicans at 12x magnification

Candida albicans at 12x magnification

Metal deposits
Rust spot on a contact lens

Rust spot on a contact lens

Soft lens, metallic foreign object with rust ring

Soft lens, metallic foreign object with rust ring

Rust spot, 200-fold, interference contrast

Rust spot, 200-fold, interference contrast

Cross-section of a contact lens through a rust spot (200-fold magnification)

Cross-section of a contact lens through a rust spot (200-fold magnification)

Metal deposit in the engraving (6-fold magnification)

Metal deposit in the engraving (6-fold magnification)

Metal deposit, 50-fold magnification, bright field

Metal deposit, 50-fold magnification, bright field

Chapter III.5: Mixed deposits – Jelly bumps
Mixed deposits – Jelly bumps
Jelly bumps on a conventional hydrophilic contact lens

Jelly bumps on a conventional hydrophilic contact lens

Jelly bumps at 6-fold magnification

Jelly bumps at 6-fold magnification

Top view of a jelly bump

Top view of a jelly bump

Sectional image of a jelly bump in a cross-section of a contact lens (200-fold)

Sectional image of a jelly bump in a cross-section of a contact lens (200-fold)